Diuretic plus ACE inhibitor reduced risk for diabetic heart disease

Using a combination of diuretics and ACE inhibitors to manage blood pressure in people with type 2 diabetes can help protect against heart disease.
The worldwide study known as ADVANCE, found that by combined therapy it reduced the risk of dying from heart disease by 18 percent.Heart disease kills two out of three people with diabetes, who are at increased risk of stroke, heart attacks and related conditions such as degenerative eye disease. Blood pressure management is recommended to reduce the risk of heart disease.

The study tracked more than 11,100 people with type 2 diabetes from 215 medical centers in 20 countries for four years.They received either a combination of the ACE inhibitor perindopril and the diuretic indapamide or a placebo.
Over the course of the four years ,the researchers found that people with the combined therapy had an average reduction in systolic blood pressure of 5-6 mm Hg and diastolic blood pressure of 2 mm Hg compared with the placebo group.This combined therapy less likely to have a heart disease event, such as stroke or heart attack, over the treatment period.If the drugs lower blood pressure as much and do not have metabolic side-effects, would be as protective as this combination treatment